药物化学总监，高级总监 (Medicinal Chemistry)

药物化学总监，高级总监 (Medicinal Chemistry) 职位描述

岗位职责：

1.  负责小分子药物新药研发团队的日常工作包括新型分子的设计，合成方案的制定、化合物的优化，专利的查新与撰写、关键技术难题的解决等小分子药物化学研发过程的管理，参与重要研发节点的监管和决策

2.  追踪国际创新发现及优化的相关平台和技术、及时掌握行业最新动态，为项目提供专业信息支持

3.  负责药物化学部团队的招聘、培训和管理，提升团队研发实力和效率

4.  负责实验室安全责任管理

任职要求：

1.  有机化学，药物化学， 计算化学等相关专业、博士学历，具有药物化学10年以上相关经验和不少于5年的药化项目领导经验、有项目成功进入临床阶段者优先，有海外制药公司或生物医药公司工作经验者优先

2.  具备解决新药研发难题的能力，包括化合物合成和优化过程中出现的各种问题，对于化合物成药性有深刻的理解，对于药代动力学和毒理有较深入的了解，能够熟练运用这些知识解决药物发现中的问题

3.  具有良好的组织协调和团队领导能力和经验，具有5年以上10人以上规模团队管理经验

4.  具有团队合作精神、良好的沟通和执行能力，具有很强的主观能动性，高度的责任感和敬业精神

Job Responsibilities:

1.    Respossible for the whole process management of small molecule drug discovery and development including:

- Design and execution of small molecule drug candidates

- Planning for chemical synthesis overall schemes

- Patents search and update

- Resolution of key technology puzzles

- Participating major decisions of R&D mile stones.

2.    Track worldwide innovative discovery and optimization from relevant platforms. Keep abreast of the latest development of the industry, provide professional information support for the project. 

3.　　 Responsible for the recruitment, training and management of medicinal chemistry team to enhance R&D capacity and efficiency.

4.　　 Responsible for laboratory EHS management

Qualifications:

1.PhD degree in organic chemistry, medicinal chemistry, computational chemistry with more than 10 years of relevant experience in medicinal chemistry and no less than 5 years of experience in drug development projects. Successful experience with projects into clinical stage is preferred. Overseas pharmaceutical companies and/or Biopharmaceutical companies working experience is a plus.

2. With strong ability to solve problems related to the hit identification and lead optimization process. With deep understanding of drugability, pharmacokinetics and toxicology of small molecule drug candidates.

3.Skillful coordination and strong team leadership experience, with more than 5 years of team management experience of more than 10 people.

4. Excellent communication and execution skills, being self-motivated, high sense of responsibility and professionalism.